The use of lipid formulations may help you to overcome aqueous solubility problems. This technology may also be used for APIs exhibiting moisture or oxygen related stability issues.
Lipid formulations are filled in hard gelatin capsules and capsules are made leak free by using a high integrity sealing technology.
Essential API properties for applying this technology:
This technology has a wide operating window. APIs should be soluble or suspensible in oil or lipid-like media; the lipophilic character may be determined by log P and/or crystallinity features.
Minimum amount of API needed for feasibility study: